30 vs 32 – What Gives? Houston’s 30^th ranked rushing attack versus Buffalo’s NFL worst 32^nd ranked run defense.  Can Slaton get going or can the Bills begin to claw their way out of the  worst ranked spot?

Who covers ‘Awesome’ Owen? Daniels poses a very real threat against the Bills’ 10^th ranked pass defense.  It will likely be a contingent of safety George Wilson, linebacker Chris Draft and safety Bryan Scott, should Scott return from an ankle injury.  Whoever it is or whatever the game plan, the Bills will have their work cut out for them.  In his last three games, Daniels has 23 catches for 295 yards and three touchdowns.

Can Super Mario ring Demetrius’s Bell? Mario Williams meet Demetrius Bell.  First pick meet the 219^th pick.  Williams is developing into a premier pass rusher while Bell is just getting his feet wet starting at the tackle.  On paper, this has mismatch all over it and the advantage goes to Williams (duh).  But that’s why the game’s not played on paper.  Bell will probably get help from Andy Levitre, but if he can hold his own against Super Mario and keep Fitzpatrick from counting clouds all day, the Bills will be in good shape.

Road Warriors vs. Home Wreckers. Houston is 2-1 away from Reliant Stadium, averaging Xbox like numbers, almost 446 yards per game while scoring 27.6 points per game on the road.  Matt Schaub has thrown for 357, 371 and 392 respectively in three road games, while throwing for 10 touchdowns compared to only two picks. The Bills, however, haven’t had a lot of success at home.  The Bills are 1-2 and have lost two consecutive home games this season to New Orleans and Cleveland, while being outscored 33-10.  It’s been eight quarters since the Bills scored a touchdown at Ralph Wilson Stadium.

Can Byrd ‘stump the Schaub?’ The reigning defensive rookie of the week, Jairus Byrd, looks to keep the magic alive against one of the AFC’s best QBs not named Brady or Manning.  Byrd recorded back to back 2-interception weeks against the Jets and Panthers and he’s got five picks in the past three weeks.  But Schaub’s no Mark Sanchez or Jake Delhomme.  While Sanchez and Delhomme might not combine to throw 16 TDs this season, we’re not at the halfway point of the season and Schaub’s already notched a franchise best 16 TDs.

Lee-der of the Pack. Your attention please.  We have a Lee Evans sighting.  Evans has caught touchdown passes in two straight weeks, and after catching just 12 passes and one touchdown in the first five weeks, Evans has caught nine balls for 143 yards and two scores against New York and Carolina the past two weeks.

6-19.  That’s Bills head coach Dick Jauron’s record against teams that had a winning record the week they played the Bills, according to Mark Gaughan of the Buffalo News.  FYI, the Houston Texans are 4-3 entering this week’s game.